Relevant publications on Dual Use
Monastersky, R. Publish and Perish? The Chronicle of Higher Education 11 Oct 2002: A16-19.
Joint Editors and Authors Group. Statement on Scientific Publication and Security. Science 299 (21 Feb): 1149, 2003.
Falkow, S and Kennedy D. Letters: Science Publishing and Security Concerns. Science 300 (2 May): 737-739, 2003 [DOI: 10.1126/science.300.5620.737e].
Petro, JB. Intelligence Support to the Life Science Community: Mitigating Threats from Bioterrorism. Studies in Intelligence 48(3) : 57-68, 2004.
Keel, BA. Protecting America's Secrets While Maintaining Academic Freedom. Academic Medicine 79 (Apr): 333-342, 2004.
Shea, DA. Balancing Scientific Publication and National Security Concerns: Issues for Congress. CRS Report for Congress. 16 Dec 2004. (RL31695).
Campbell, P. Dual-use results and scientific journals. National Scientific Advisory Board for Biosecurity: Inaugural Meeting. Hyatt Regency, Bethesda MD. 30 Jul 2005. PPT | transcript
Jackson IL-4 Mousepox Case
Jackson, RJ, et al. Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox. Journal of Virology 75 (Feb):1205-1210, 2001 [DOI: 10.1128/JVI.75.3.1205-1210.2001].
Nowak, R. Disaster in the making: An engineered mouse virus leaves us one step away from the ultimate bioweapon. New Scientist 169 (13 Jan): 4-6, 2001.
Cohen, J. Designer Bugs. Atlantic Monthly 290 (Jul/Aug): 113-123, 2002.
Rosengard et al. Variola Case
Rosengard, AM, Liu, Y, Nie, Z, & Jimenez, R. Variola virus immune evasion design: Expression of a highly efficient inhibitor of human complement. PNAS 99 (25 Jun): 8808-8813, 2002.
Lachmann, PJ. Microbial subversion of the immune response. PNAS 99 (25 Jun): 8461 - 8462, 2002.
Cozzarelli, NR. PNAS policy on publication of sensitive material in the life sciences. PNAS 100 (18 Feb): 1463-1463, 2003.
Wimmer Poliovirus Case
Cello, J., Paul, A. V. & Wimmer, E. Chemical Synthesis of Poliovirus cDNA: Generation of Infectious Virus in the Absence of Natural Template. Science 297 (9 Aug): 1016-1018, 2002.
Weldon, D. H.Res.514: Expressing serious concern regarding the publication of instructions on how to create a synthetic human polio virus. 26 Jul 2002.
Couzin, J. A Call for Restraint on Biological Data. Science 297 (2 Aug): 749-51, 2002.
Botilnum Toxin in Milk Supply Case
Russo, E. PNAS Heeds HHS Request, Delays Publication of Sensitive Research. Research Policy Alert 7 Jun 2005.
Editorial: Risks and benefit of dual-use research. Nature 435 (16 Jun): 855, 2005.
Russo, E. PNAS Publishes Bioterror Botulinum Toxin Paper Despite HHS Objections. Research Policy Alert 29 Jun 2005.
Wein, LM & Liu, Y. Analyzing a bioterror attack on the food supply: The case of botulinum toxin in milk. PNAS 102 (12 Jul): 9984-9989, 2005 [DOI: 10.1073/pnas.0408526102].
Alberts, B. Editorial: Modeling attacks on the food supply. PNAS 102 (12 Jul): 9737-9738, 2005 [DOI: 10.1073/pnas.0504944102].
1918 Flu Case
Tumpey, TM et al. Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus. Science 310 (7 Oct): 77-80, 2005 [DOI: 10.1126/science.1119392].
Sharp, PA. 1918 Flu and Responsible Science. Science 310 (7 Oct): 17, 2005 [DOI: 10.1126/science.310.5745.17].
Taubenberger, JK. Characterization of the 1918 influenza virus polymerase genes. Nature 437 (6 Oct): 889-893, 2005 [DOI: 10.1038/nature04230].
von Bubnoff, A. The 1918 flu virus is resurrected. Nature 437 (6 Oct): 794-795, 2005 [DOI: 10.1038/437794a].
Russo E. 1918 Flu Papers Test HHS' Ability to Efficiently Monitor Pre-Publication Dual-Use Research. Research Policy Alert 6 Oct 2005.
Kurzweil, R, & Joy, B. Recipe for Destruction. New York Times 17 Oct 2005: A19.
Russo, E. Biosecurity Advisory Board Reports Lessons Learned from 1918 Flu Papers; Aims to Improve Screening Process. Research Policy Alert. 23 Nov 2005.
Aldhous P. Biologists risk becoming accidental terrorists. New Scientist v190 n2555 (10 June 2006) 24.
Editorial: Towards Better Biosecurity. Nature v440 n715 (6 April 2006) 715.
Relman DA, Choffnes E, and Lemon SM. In Search of Biosecurity. Science v311 n5769 (31 March 2006) 1835
National Academies
Globalization, Biosecurity, and the Future of the Life Sciences. Commmittee on Advances in Technology and the Prevention of Their Application to Next Generation Biowarfare Threats, National Research Council (2006).
Biotechnology Research in an Age of Terrorism. Committee on Research Standards and Practices to Prevent the Destructive Application of Biotechnology, National Research Council (2004).
